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KMID : 0370219830270040283
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Yakhak Hoeji
1983 Volume.27 No. 4 p.283 ~ p.287
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Syntheses and Central Nervous Depressant Activities of Piperine Derivatives (II) Piperic Acid Amides
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은재순/Eun JS
임중기/김완주/우원식/이은방/Rim JK/Kim WJ/Woo WS/Lee EB
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Abstract
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In order to search more active and less toxic central nervous depressants, piperic acid amides were synthesized by condensation of piperonal with crotonic acid amides. The bioassay results revealed that, among the compounds synthesized, the piperonic acid methylamide and ethylamide exhibited potent protective activity against strychnine-induced convulsion.
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